Home > Products > CD19 & CD28 > Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scDiabody-CH3)

Recombinant Human Anti-CD19 x Human Anti-CD28 Bispecific Antibody (scDiabody-CH3)  (SCDBC-H217)

Recombinant Anti-CD19 x Anti-CD28 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD19/anti-CD28 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Specifications

Targets
CD19 & CD28
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD19
Host Animal 1
Human
Target 2
CD28
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma; Follicular lymphoma; Leukemia

Targets

Target 1
CD19
Gene ID
UniProt ID
Alternative Names
CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Target 2
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

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