Home > Products > CD19 & CD3 > Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Bibody)

Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Bibody)  (BIBD-H218)

Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-CD19 specificity is fused to the anti-CD19 heavy or light chain of the Fab. This BsAb can retarget T cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Specifications
Targets
CD19 & CD3
Type
Bibody
Species Reactivity
Human
Target 1
CD19
Host Animal 1
Mouse
Target 2
CD3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma; Follicular lymphoma; Leukemia
Targets
Target 1
CD19
Gene ID
UniProt ID
Alternative Names
CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

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