Name: Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc)
SKU: BSFVF-041
Rating: 5 (1 reviews)

Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CD19/CD3 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

CD19 & CD3

Type

Tandem scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma; Follicular lymphoma; Leukemia

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD19

Gene ID

930

UniProt ID

P15391

Alternative Names

CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4

Target 2

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc) (BSFVF-041). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc) (CAT#: BSFVF-041)

Specifications

Targets

Customer Reviews and Q&As