Home > Products > CD19 & CD64 > Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (IgG-scFv)

Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (IgG-scFv)  (IGFV-044)

Recombinant Anti-CD19 x Anti-CD64 Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget neutrophils to tumor cells. It is designed for the research of B cell lymphoma; Leukemia therapy.

Specifications

Targets
CD19 & CD64
Type
IgG-scFv
Species Reactivity
Human
Target 1
CD19
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma; Leukemia

Targets

Target 1
CD19
Gene ID
UniProt ID
Alternative Names
CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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