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Recombinant Human Anti-CD19 x Human Anti-CD89 Bispecific Antibody (Miniantibody)  (CAT#: MNAB-H222)

Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD19 antibody variable domain is linked to another scFv of an anti-CD89 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget macrophages to tumor cells. It is designed for the research of B cell lymphoma; Leukemia therapy.
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Specifications

Targets
CD19 & CD89
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma; Leukemia

Targets

Target 1
CD19
Gene ID
UniProt ID
Alternative Names
CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Target 2
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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