Home > Products > CD19 & CD89 > Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Minibody)

Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Minibody)  (MiniB-045)

Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD19 scFv fused to N-terminus of Knob-CH3 domain and the anti-CD89 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget macrophages to tumor cells. It is designed for the research of B cell lymphoma; Leukemia therapy.

Specifications

Targets
CD19 & CD89
Type
Minibody
Species Reactivity
Human
Target 1
CD19
Host Animal 1
Mouse
Target 2
CD89
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma; Leukemia

Targets

Target 1
CD19
Gene ID
UniProt ID
Alternative Names
CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Target 2
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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