Home > Products > CD19 & CD89 > Recombinant Human Anti-CD19 x Anti-CD89 Bispecific Antibody (Tandem Fab)

Recombinant Human Anti-CD19 x Anti-CD89 Bispecific Antibody (Tandem Fab)  (BSFAB-H220)

Recombinant Anti-CD19 x Anti-CD89 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-CD19 and anti-CD89 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget macrophages to tumor cells. It is designed for the research of B cell lymphoma; Leukemia therapy.

Specifications

Targets
CD19 & CD89
Type
Tandem Fab
Species Reactivity
Human
Target 1
CD19
Host Animal 1
Human
Target 2
CD89
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphomaLeukemia

Targets

Target 1
CD19
Gene ID
UniProt ID
Alternative Names
CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
Target 2
CD89
Gene ID
UniProt ID
Alternative Names
FcαRI; FCAR; Fc fragment of IgA, receptor for; CD89; FcalphaRI; immunoglobulin alpha Fc receptor; Fc alpha receptor

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