Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Diabody-Fc) (BSDBF-193)

Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CD2 and anti-CD4 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block two antigens simultaneously. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet INQUIRY

Specifications

Targets

CD2 & CD4

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Targets

Target 1

CD2

Gene ID

914

UniProt ID

P06729

Alternative Names

CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

Target 2

CD4

Gene ID

920

UniProt ID

B4DT49

Alternative Names

CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-193)

Specifications

Targets

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