Home > Products > CD2 & CD4 > Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Diabody-Fc)

Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Diabody-Fc)  (BSDBF-H355)

Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CD2 and anti-CD4 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block two antigens simultaneously. It is designed for the research of HIV-1 infection, AIDS therapy.

Specifications

Targets
CD2 & CD4
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD2
Host Animal 1
Human
Target 2
CD4
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS

Targets

Target 1
CD2
Gene ID
UniProt ID
Alternative Names
CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
Target 2
CD4
Gene ID
UniProt ID
Alternative Names
CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3

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