Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) (FABVC-H355)

Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD2 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD4 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can block two antigens simultaneously. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet INQUIRY

Specifications

Targets

CD2 & CD4

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Targets

Target 1

CD2

Gene ID

914

UniProt ID

P06729

Alternative Names

CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

Target 2

CD4

Gene ID

920

UniProt ID

B4DT49

Alternative Names

CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-H355)

Specifications

Targets

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