Home > Products > CD2 & TCR (Vβ8) > Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-Fc)

Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-Fc)  (BSDBF-048)

Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CD2 and anti-TCR (Vβ8) antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can activate T cells. It is designed for the research of Tumors therapy.

Specifications
Targets
CD2 & TCR (Vβ8)
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Mouse
Target 1
CD2
Host Animal 1
Mouse
Target 2
TCR (Vβ8)
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD2
Gene ID
UniProt ID
Alternative Names
CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
Target 2
TCR (Vβ8)
Gene ID
Alternative Names
Trbv8; T cell receptor beta variable 8; TCR; T-cell receptor

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