Home > Products > CD20 & CD22 > Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG)

Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG)  (FABIG-H224)

Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb is designed for the research of Lymphoma; Leukemia; Antoimmune disease; Immune dysfunction disease therapy.

Specifications
Targets
CD20 & CD22
Type
Fab-IgG
Species Reactivity
Human
Target 1
CD20
Host Animal 1
Human
Target 2
CD22
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma; Leukemia; Antoimmune disease; Immune dysfunction disease
Targets
Target 1
CD20
Gene ID
UniProt ID
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD22
Gene ID
UniProt ID
Alternative Names
CD22; CD22 molecule; Cluster of differentiation 22; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

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