Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD20 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD22 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb is designed for the research of Lymphoma; Leukemia; Antoimmune disease; Immune dysfunction disease therapy.
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