Home > Products > CD20 & CD28 > Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-Fc)

Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-Fc)  (BSCFV-H227)

Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD20 specificity or anti-CD28 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lymphoma therapy.

Specifications

Targets
CD20 & CD28
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD20
Host Animal 1
Mouse
Target 2
CD28
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma

Targets

Target 1
CD20
Gene ID
UniProt ID
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

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