Home > Products > CD20 & CD28 > Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-IgG)

Recombinant Human Anti-CD20 x Human Anti-CD28 Bispecific Antibody (scFv-IgG)  (BSSG-H227)

Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD20 antibody variable domain are respectively connected to the N terminus of the anti-CD28 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lymphoma therapy.

Specifications
Targets
CD20 & CD28
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD20
Host Animal 1
Human
Target 2
CD28
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma
Targets
Target 1
CD20
Gene ID
UniProt ID
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

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