Home > Products > CD20 & CD28 > Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body)

Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body)  (TRIB-050)

Recombinant Anti-CD20 x Anti-CD28 Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-CD20 antibody are both extended with the scFv fragment from an anti-CD28 antibody. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lymphoma therapy.

Datasheet
Specifications
Targets
CD20 & CD28
Type
Triple Body
Species Reactivity
Human
Target 1
CD20
Host Animal 1
Mouse
Target 2
CD28
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma
Targets
Target 1
CD20
Gene ID
931
UniProt ID
A0A024R507
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD28
Gene ID
940
UniProt ID
P10747
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

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