Home > Products > CD20 & CD3 > Recombinant Human Anti-CD20 x Human Anti-CD3 Bispecific Antibody (Miniantibody)

Recombinant Human Anti-CD20 x Human Anti-CD3 Bispecific Antibody (Miniantibody)  (MNAB-H228)

Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD20 antibody variable domain is linked to another scFv of an anti-CD3 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lymphoma therapy.

Specifications
Targets
CD20 & CD3
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD20
Host Animal 1
Mouse
Target 2
CD3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma
Targets
Target 1
CD20
Gene ID
UniProt ID
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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