Home > Products > CD20 & CD3 > Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (scDiabody-CH3)

Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (scDiabody-CH3)  (SCDBC-051)

Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD20/anti-CD3 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lymphoma therapy.

Specifications
Targets
CD20 & CD3
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD20
Host Animal 1
Mouse
Target 2
CD3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma
Targets
Target 1
CD20
Gene ID
UniProt ID
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

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