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Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (VHH-IgG)  (CAT#: BSSG-365)

Recombinant Anti-CD20 x Anti-CD47 Bispecific Antibody (VHH-IgG) is formed by an IgG and two VHH fragments. The VHHs from an anti-CD47 antibody variable domain are respectively connected to the N terminus of the anti-CD20 IgG heavy chains or light chains to form VHH-(H)IgG or VHH-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget macrophages to tumor cells. It is designed for the research of Lymphoma therapy.
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Specifications

Targets
CD20 & CD47
Type
Appended IgGs
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma

Targets

Target 1
CD20
Gene ID
UniProt ID
Alternative Names
MS4A1; membrane-spanning 4-domains, subfamily A, member 1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; B-lymphocyte antigen CD20; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1
Target 2
CD47
Gene ID
UniProt ID
Alternative Names
CD47; CD47 molecule; IAP; OA3; MER6; leukocyte surface antigen CD47; CD47 glycoprotein; Rh-related antigen; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; antigenic surface determinant protein OA3; antigen identified by monoclonal antibody 1D8; CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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