Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-CH3) (BSFC-053)

Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD22 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-saporin scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Lymphoma therapy.

Datasheet INQUIRY

Specifications

Targets

CD22 & saporin

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Pretargeting system for immunotoxin delivery

Related Disease

Lymphoma

Targets

Target 1

CD22

Gene ID

933

UniProt ID

P20273

Alternative Names

CD22; CD22 molecule; Cluster of differentiation 22; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Target 2

saporin

Alternative Names

Saporin; Ribosome inactivating protein; RIP

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD22 x Anti-saporin Bispecific Antibody (scFv-CH3) (CAT#: BSFC-053)

Specifications

Targets

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