Recombinant Anti-CD28 x Anti-CD3 VHH BispecificAntibody (Bibody) (BIBD-366)

Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Bibody) is a Fab-VHH format that uses heterodimeric Fab as a scaffold, and a VHH region linked to one of its heavy (Fd) or light (L) chain. The VHH of the anti-CD3 specificity is fused to the anti-CD28 heavy or light chain of the Fab. This BsAb can improve T-cell activation. It is designed for the research of Tumors therapy.

Datasheet

Specifications

Targets

CD28 & CD3

Type

Bibody

Species Reactivity

Human

Target 1

CD28

Host Animal 1

Mouse

Target 2

CD3

Host Animal 2

llama

Application

FuncS; Promising therapeutic agent

Related Disease

Tumors

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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