Home > Products > CD28 & CD3 > Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Minibody)

Recombinant Human Anti-CD28 x Human Anti-CD3 Bispecific Antibody (Minibody)  (MiniB-H230)

Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD28 scFv fused to N-terminus of Knob-CH3 domain and the anti-CD3 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can improve T-cell activation. It is designed for the research of Tumors therapy.

Specifications
Targets
CD28 & CD3
Type
Minibody
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Human
Target 2
CD3
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
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