Name: Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-CH3)
SKU: BSFC-054
Rating: 5 (1 reviews)

Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD28 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD3 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can improve T-cell activation. It is designed for the research of Tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & CD3

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD28 x Anti-CD3 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-054)

Specifications

Targets

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