Home > Products > CD28 & CD30 > Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Triple Body)

Recombinant Human Anti-CD28 x Anti-CD30 Bispecific Antibody (Triple Body)  (TRIB-H231)

Recombinant Anti-CD28 x Anti-CD30 Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-CD28 antibody are both extended with the scFv fragment from an anti-CD30 antibody. This BsAb can retarget T cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

Specifications

Targets
CD28 & CD30
Type
Triple Body
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Human
Target 2
CD30
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)

Targets

Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
CD30
Gene ID
UniProt ID
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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