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Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-CH1/CL) (CAT#: BSCC-056)
Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-CD28 antibody variable domain is fused to CH1 and the other scFv from an anti-CD40 antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can increase T-cell proliferation, induce DC maturation and prime efficacy of cytotoxic T cells. It is designed for the research of Acute myeloid leukaemic (AML) therapy.
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