Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-Fc) (BSCFV-056)

Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD28 specificity or anti-CD40 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can increase T-cell proliferation, induce DC maturation and prime efficacy of cytotoxic T cells. It is designed for the research of Acute myeloid leukaemic (AML) therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & CD40

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myeloid leukaemic (AML)

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

CD40

Gene ID

958

UniProt ID

P25942

Alternative Names

CD40 molecule; CD40; p50; Bp50; Cluster of differentiation 40; CDW40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-056)

Specifications

Targets

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