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Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Diabody)  (CAT#: T-BSDB-056)

Recombinant Anti-CD28 x Anti-CD40 Bispecific Antibody (Tandem Diabody) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb can increase T-cell proliferation, induce DC maturation and prime efficacy of cytotoxic T cells. It is designed for the research of Acute myeloid leukaemic (AML) therapy.
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Specifications

Targets
CD28 & CD40
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Acute myeloid leukaemic (AML)

Targets

Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
CD40
Gene ID
UniProt ID
Alternative Names
CD40 molecule; CD40; p50; Bp50; Cluster of differentiation 40; CDW40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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