Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) (SCDB-H231)

Recombinant Anti-CD28 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget T cells to tumor cells. It is designed for the research of Glioblastoma; Squamous cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & CD44

Type

Single-chain Diabody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Glioblastoma; Squamous cancer

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

CD44

Gene ID

960

UniProt ID

P16070

Alternative Names

CD44; CD44 antigen; ECMRIII; Extracellular matrix receptor III; HCAM; Homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; HUTCH-1; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD28 x Anti-CD44 Bispecific Antibody (Single-chain Diabody) (CAT#: SCDB-H231)

Specifications

Targets

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