Home > Products > CD28 & CSPG4 > Recombinant Human Anti-CD28 x Human Anti-CSPG4 Bispecific Antibody (Miniantibody)

Recombinant Human Anti-CD28 x Human Anti-CSPG4 Bispecific Antibody (Miniantibody)  (MNAB-H239)

Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD28 antibody variable domain is linked to another scFv of an anti-CSPG4 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma therapy.

Specifications

Targets
CD28 & CSPG4
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
CSPG4
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma

Targets

Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
CSPG4
Gene ID
UniProt ID
Alternative Names
NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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