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Recombinant Human Anti-CD28 x Human Anti-CSPG4 Bispecific Antibody (scIgG)  (CAT#: SCIGG-H239)

Recombinant Anti-CD28 x Anti-CSPG4 Bispecific Antibody (scIgG) is designed to be expressed as two chains, each chain has the same units with their parental IgG antibodies, anti-CD28 and anti-CSPG4 IgGs. The two chains form heterodimer via Fc KIH technology. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma therapy.
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Specifications

Targets
CD28 & CSPG4
Type
Single chain IgGs
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma

Targets

Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
CSPG4
Gene ID
UniProt ID
Alternative Names
NG2; Neuron-glial antigen 2; Melanoma-associated chondroitin sulfate proteoglycan; chondroitin sulfate proteoglycan 4; CSPG4; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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