Recombinant Human Anti-CD28 x Human Anti-FOLR1 Bispecific Antibody (Bibody) (BIBD-H236)

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-CD28 specificity is fused to the anti-CD28 heavy or light chain of the Fab. This BsAb can retarget T cells to tumor cells. It is designed for the research of Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & FOLR1

Type

Bibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Ovarian cancer; Solid tumors

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

FOLR1

Gene ID

2348

UniProt ID

A0A024R5H1

Alternative Names

FOLR1; folate receptor 1 (adult); folate receptor 1; FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD28 x Human Anti-FOLR1 Bispecific Antibody (Bibody) (CAT#: BIBD-H236)

Specifications

Targets

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