Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG(L)-scFv) (IGLFV-060)

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CD28 antibody are fused to the C terminus of an anti-FOLR1 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget T cells to tumor cells. It is designed for the research of Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & FOLR1

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Ovarian cancer; Solid tumors

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

FOLR1

Gene ID

2348

UniProt ID

A0A024R5H1

Alternative Names

FOLR1; folate receptor 1 (adult); folate receptor 1; FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG(L)-scFv) (IGLFV-060). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-060)

Specifications

Targets

Customer Reviews and Q&As