Home > Products > CD28 & FOLR1 > Recombinant Human Anti-CD28 x Human Anti-FOLR1 Bispecific Antibody (scDiabody-Fc)

Recombinant Human Anti-CD28 x Human Anti-FOLR1 Bispecific Antibody (scDiabody-Fc)  (SCDBF-H236)

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD28/anti-FOLR1 diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Ovarian cancer; Solid tumors therapy.

Specifications
Targets
CD28 & FOLR1
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Human
Target 2
FOLR1
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Ovarian cancer; Solid tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
FOLR1
Gene ID
UniProt ID
Alternative Names
FOLR1; folate receptor 1 (adult); folate receptor 1; FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18
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