Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (F(ab')2-scFv2) (BABFV-H237)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD28 specificity is fused to the C terminus of the anti-HN Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & HN

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising preventive/therapeutic agent

Related Disease

Tumors

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

Gene ID

912270

UniProt ID

Q9Q2W5

Alternative Names

Hemagglutinin-neuraminidase; HN

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-H237)

Specifications

Targets

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