Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Fab-scFv-Fc) (FABVC-H237)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD28 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-HN to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & HN

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising preventive/therapeutic agent

Related Disease

Tumors

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

Gene ID

912270

UniProt ID

Q9Q2W5

Alternative Names

Hemagglutinin-neuraminidase; HN

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Fab-scFv-Fc) (FABVC-H237). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-H237)

Specifications

Targets

Customer Reviews and Q&As