Home > Products > CD28 & HN > Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scDiabody-Fc)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scDiabody-Fc)  (SCDBF-061)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD28/anti-HN diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Specifications
Targets
CD28 & HN
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
HN
Host Animal 2
Mouse
Application
FuncS; Promising preventive/therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
HN
Gene ID
UniProt ID
Alternative Names
Hemagglutinin-neuraminidase; HN
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