Home > Products > CD28 & HN > Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv-Fc)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv-Fc)  (BSCFV-H237)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD28 specificity or anti-HN specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Specifications
Targets
CD28 & HN
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
HN
Host Animal 2
Mouse
Application
FuncS; Promising preventive/therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
HN
Gene ID
UniProt ID
Alternative Names
Hemagglutinin-neuraminidase; HN

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