Home > Products > CD28 & HN > Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Tandem scFv-Fc)

Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-H237)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CD28/HN tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Specifications
Targets
CD28 & HN
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Human
Target 2
HN
Host Animal 2
Human
Application
FuncS; Promising preventive/therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
HN
Gene ID
UniProt ID
Alternative Names
Hemagglutinin-neuraminidase; HN
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