Name: Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (sdAb-IgG)
SKU: BSSG-368
Rating: 5 (1 reviews)

Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (sdAb-IgG) is formed by an IgG and two single domains antibodies (sdAbs). The sdAbs from an anti-MUC1 antibody variable domain are respectively connected to the N terminus of the anti-CD28 IgG heavy chains or light chains to form sdAb-(H)IgG or sdAb-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Pancreatic cancer; Ovarian cancer; Breast cancer; Bile duct cancer (BDC) therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & MUC1

Type

sdAb-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Pancreatic cancer; Ovarian cancer; Breast cancer; Bile duct cancer (BDC)

Host Animal 1

Mouse

Host Animal 2

llama

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

MUC1

Gene ID

4582

UniProt ID

P15941

Alternative Names

MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD28 x Anti-MUC1 Bispecific Antibody (sdAb-IgG) (CAT#: BSSG-368)

Specifications

Targets

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