Name: Recombinant Human Anti-CD3 x Mouse Anti-B7H3 Bispecific Antibody (IgG-scFv)
SKU: KN-0724-N1
Rating: 5 (1 reviews)

Recombinant Human Anti-CD3 x Mouse Anti-B7H3 Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. The mouse anti-CD3 scFvs are fused to the C terminus of the anti-B7H3 IgG-Fc chain. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & B7H3

Type

IgG-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Solid tumors

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

B7H3

Gene ID

80381

UniProt ID

Q5ZPR3

Alternative Names

B7H3; B7 homolog 3; CD276; CD276 molecule; B7-H3; B7RP-2; 4Ig-B7-H3; B7-related protein 2; B7RP2; B7 homologue 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD3 x Mouse Anti-B7H3 Bispecific Antibody (IgG-scFv) (CAT#: KN-0724-N1)

Specifications

Targets

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