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Recombinant Human Anti-CD3 x Anti-B7H3 Bispecific Antibody (Triple Body)  (TRIB-H240)

Recombinant Anti-CD3 x Anti-B7H3 Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-CD3 antibody are both extended with the scFv fragment from an anti-B7H3 antibody. This BsAb can retarget T cells to tumor cells. It is designed for the research of Solid tumors therapy.

Specifications

Targets
CD3 & B7H3
Type
Triple Body
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Human
Target 2
B7H3
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
B7H3
Gene ID
UniProt ID
Alternative Names
B7H3; B7 homolog 3; CD276; CD276 molecule; B7-H3; B7RP-2; 4Ig-B7-H3; B7-related protein 2; B7RP2; B7 homologue 3

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