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Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Bibody)  (CAT#: BIBD-H254)

Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-CD3 specificity is fused to the anti-CD3 heavy or light chain of the Fab. This BsAb can retarget T cells to tumor cells. It is designed for the research of Solid tumors therapy.
Datasheet INQUIRY

Specifications

Targets
CD3 & CD248
Type
Bibody
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD248
Gene ID
UniProt ID
Alternative Names
CD248; CD248 molecule, endosialin; TEM1; CD164L1; endosialin; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; tumor endothelial marker 1
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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