Home > Products > CD3 & CD248 > Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Fab-scFv-Fc)

Recombinant Human Anti-CD3 x Human Anti-CD248 Bispecific Antibody (Fab-scFv-Fc)  (FABVC-H254)

Recombinant Anti-CD3 x Anti-CD248 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD3 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD248 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to tumor cells. It is designed for the research of Solid tumors therapy.

Specifications
Targets
CD3 & CD248
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Human
Target 2
CD248
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD248
Gene ID
UniProt ID
Alternative Names
CD248; CD248 molecule, endosialin; TEM1; CD164L1; endosialin; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; tumor endothelial marker 1

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Heidenkampsweg 58, 20097 Hamburg, Germany
Tel: 44-207-097-1828
Email:
Related products of "CD3 & CD248"
45-1 Ramsey Road, Shirley, NY 11967, USA 1-631-381-2994 1-631-207-8356
24x7 CUSTOMER SERVICE
Easy access to products and services you need from our library via
powerful searching tools
© 2007 - 2020 Creative-Biolabs All Rights Reserved.
Distributors
To view the contact information for a specific location,
select your country or region: