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Recombinant Human Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv)  (CAT#: BSFV-H239)

Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv from an anti-CD3 antibody variable domains fused with a scFv from an anti-CD30 antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget T cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.
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Specifications

Targets
CD3 & CD30
Type
Tandem scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD30
Gene ID
UniProt ID
Alternative Names
CD30; TNFRSF8; tumor necrosis factor receptor superfamily member 8; TNF receptor superfamily member 8; CD30; Ki-1; D1S166E
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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