Home > Products > CD3 & CD30 > Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv-Fc)

Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-065)

Recombinant Anti-CD3 x Anti-CD30 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CD3/CD30 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

Specifications
Targets
CD3 & CD30
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Mouse
Target 2
CD30
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD30
Gene ID
UniProt ID
Alternative Names
CD30; TNFRSF8; tumor necrosis factor receptor superfamily member 8; TNF receptor superfamily member 8; CD30; Ki-1; D1S166E
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