Name: Recombinant Mouse Anti-CD3 x Human Anti-CD33 Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N37
Rating: 5 (1 reviews)

ecombinant Mouse Anti-CD3 x Human Anti-CD33 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of mouse anti-CD3 and human anti-CD33 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget T cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & CD33

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer

Host Animal 1

Mouse

Host Animal 2

Human

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD33

Gene ID

945

UniProt ID

P20138

Alternative Names

CD33; CD33 molecule; Cluster of differentiation 33; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Mouse Anti-CD3 x Human Anti-CD33 Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N37)

Specifications

Targets

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