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Recombinant Anti-CD3 sdAb x Anti-CD38 sdAb Bispecific Antibody (Bi-sdAb)  (CAT#: BIVHH-052)

Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (Bi-sdAb) is designed to be expressed as a sdAb from anti-CD3 antibody variable domains fused with a sdAb from an anti-CD38 antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget T cells to CD38+ cancer cells. It is designed for the research of Multiple myeloma (MM) therapy.
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Specifications

Targets
CD3 & CD38
Type
Bi-sdAb
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Multiple myeloma (MM)
Host Animal 1
Llama
Host Animal 2
Llama

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD38
Gene ID
UniProt ID
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolaseCD59; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane inhibitor of reactive lysis; membrane attack complex inhibition factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by monoclonal antibody 16.3A5; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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