Home > Products > CD3 & CD38 > Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (F(ab')2-scFv2)

Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (F(ab')2-scFv2)  (BABFV-192)

Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD3 specificity is fused to the C terminus of the anti-CD38 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can block two receptors simultaneously. It is designed for the research of Multiple myeloma (MM) therapy.

Specifications
Targets
CD3 & CD38
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Mouse
Target 2
CD38
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Multiple myeloma (MM)
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD38
Gene ID
UniProt ID
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolaseCD59; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane inhibitor of reactive lysis; membrane attack complex inhibition factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by monoclonal antibody 16.3A5; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
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