Name: Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (sdAb-Fc-sdAb)
SKU: HCAB-052
Rating: 5 (1 reviews)

Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (sdAb-Fc-sdAb, Tetravalent Heavy Chain-only Antibody, Tetravalent HCAb) is symmetric protein with two pairs of single domain antibodies (sdAb), from anti-CD3 and anti-CD38 antibodies, fused to the N-terminus and C-terminus of the Fc separately. This BsAb is bispecific, tetravelant, 2+2 antigen-binding valency. It can retarget T cells to CD38+ cancer cells. It is designed for the research of Multiple myeloma (MM) therapy.

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Specifications

Targets

CD3 & CD38

Type

sdAb-Fc-sdAb

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Host Animal 1

Llama

Host Animal 2

Llama

Targets

Target 1

CD3

Gene ID

2064

UniProt ID

P04626

Alternative Names

ERBB2; erb-b2 receptor tyrosine kinase 2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; human epidermal growth factor receptor 2; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

Target 2

CD38

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD3 x Anti-CD38 Bispecific Antibody (sdAb-Fc-sdAb) (CAT#: HCAB-052)

Specifications

Targets

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