Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) (BABFV-H243)

Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD3 specificity is fused to the C terminus of the anti-CD4 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget T cells to HIV-1 infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & CD4

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD4

Gene ID

920

UniProt ID

B4DT49

Alternative Names

CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) (BABFV-H243). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-H243)

Specifications

Targets

Customer Reviews and Q&As